Saints Cosmas and Damian († c. ad 287) were twin brothers, physicians, and early Christian martyrs suffered martyrdom in Syria during the persecution of Emperor Diocletian. They were venerated as early as the 4th century, when churches dedicated to them were established at Jerusalem, in Egypt, and in Mesopotamia. They are Holy Patrons of surgeons, physicians, dentists, protectors of children, barbers, pharmacists, veterinarians, orphanages, day-care centers, confectioners, children in the house, against hernia, and against the plague.